中国抗癌协会

【主编】

何 悦  上海交通大学医学院附属第九人民医院

【副主编】

李 一   四川大学华西口腔医院

刘 冰   武汉大学口腔医院

彭 歆   北京大学口腔医院

王延安   上海交通大学医学院附属第九人民医院

杨新杰   空军军医大学第三附属医院

【编委】（按姓氏拼音排序）

丁昊然   四川大学华西口腔医院

杜 仲   上海交通大学医学院附属第九人民医院

胡镜宙   上海交通大学医学院附属第九人民医院

黄明伟   北京大学口腔医院

曲行舟   上海交通大学医学院附属第九人民医院

单小峰   北京大学口腔医院

沈淑坤   上海交通大学医学院附属第九人民医院

魏建华   空军军医大学第三附属医院

闫 冰   四川大学华西口腔医院

杨子桧   空军军医大学第三附属医院

章文博   北京大学口腔医院

张士剑   上海交通大学医学院附属第九人民医院

周 榕   上海交通大学医学院附属第九人民医院

钟亚华   武汉大学中南医院

朱桂全   四川大学华西口腔医院

张卓远   四川大学华西口腔医院

参考文献（References）

[1]Arora R, Cao C, Kumar M, et al. Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response [J]. Nat Commun, 2023, 14(1): 5029.

[2]Bai H, Yang J, Meng S, et al. Oral Microbiota-Driven Cell Migration in Carcinogenesis and Metastasis [J]. Front Cell Infect Microbiol, 2022, 12: 864479.

[3]Delaunay S, Pascual G, Feng B, et al. Mitochondrial RNA modifications shape metabolic plasticity in metastasis [J]. Nature, 2022, 607(7919): 593-603.

[4]Dong J, Li J, Li Y, et al. Transcriptional super-enhancers control cancer stemness and metastasis genes in squamous cell carcinoma [J]. Nat Commun, 2021, 12(1): 3974.

[5]Galeano Nino J L, Wu H, LaCourse K D, et al. Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer [J]. Nature, 2022, 611(7937): 810-7.

[6]Pascual G, Dominguez D, Elosua-Bayes M, et al. Dietary palmitic acid promotes a prometastatic memory via Schwann cells [J]. Nature, 2021, 599(7885): 485-90.

[7]Gu Z, Yao Y, Yang G, et al. Pharmacogenomic landscape of head and neck squamous cell carcinoma informs precision oncology therapy [J]. Sci Transl Med, 2022, 14(661): eabo5987.

[8]Yoon Y J, Kim D, Tak K Y, et al. Salivary gland organoid culture maintains distinct glandular properties of murine and human major salivary glands [J]. Nat Commun, 2022, 13(1): 3291.

[9]Zheng D W, Deng W W, Song W F, et al. Biomaterial-mediated modulation of oral microbiota synergizes with PD-1 blockade in mice with oral squamous cell carcinoma [J]. Nat Biomed Eng, 2022, 6(1): 32-43.

[10]Goldberg M, Manzi A, Birdi A, et al. A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer [J]. Nat Commun, 2022, 13(1): 4829.

[11]Chen W, Chen X, Wang L, et al. TIPE3 represses head and neck squamous cell carcinoma progression via triggering PGAM5 mediated mitochondria dysfunction [J]. Cell Death Dis, 2023, 14(4): 251.

[12]Qin Z, Zhang W, Liu S, et al. PVT1 inhibition stimulates anti-tumor immunity, prevents metastasis, and depletes cancer stem cells in squamous cell carcinoma [J]. Cell Death Dis, 2023, 14(3): 187.

[13]Yang Q C, Wang S, Liu Y T, et al. Targeting PCSK9 reduces cancer cell stemness and enhances antitumor immunity in head and neck cancer [J]. iScience, 2023, 26(6): 106916.

[14]Dai Y, Wang Z, Xia Y, et al. Integrative Single-Cell and Bulk Transcriptomes Analyses Identify Intrinsic HNSCC Subtypes with Distinct Prognoses and Therapeutic Vulnerabilities [J]. Clin Cancer Res, 2023, 29(15): 2845-58.

[15]Fu Q, Chen Y, Li Z, et al. A deep learning algorithm for detection of oral cavity squamous cell carcinoma from photographic images: A retrospective study [J]. EClinicalMedicine, 2020, 27: 100558.

[16]Dittberner A, Rodner E, Ortmann W, et al. Automated analysis of confocal laser endomicroscopy images to detect head and neck cancer [J]. Head Neck, 2016, 38 Suppl 1: E1419-26.

[17]Dong F, Tao C, Wu J, et al. Detection of cervical lymph node metastasis from oral cavity cancer using a non-radiating, noninvasive digital infrared thermal imaging system [J]. Sci Rep, 2018, 8(1): 7219.

[18]Kearney V, Chan J W, Valdes G, et al. The application of artificial intelligence in the IMRT planning process for head and neck cancer [J]. Oral Oncol, 2018, 87: 111-6.

[19]Pan X, Zhang T, Yang Q, et al. Survival prediction for oral tongue cancer patients via probabilistic genetic algorithm optimized neural network models [J]. Br J Radiol, 2020, 93(1112): 20190825.

[20]Hong D S, Van Tine B A, Biswas S, et al. Autologous T cell therapy for MAGE-A4(+) solid cancers in HLA-A*02(+) patients: a phase 1 trial [J]. Nat Med, 2023, 29(1): 104-14.

[21]Iwami K, Fujii M, Nishio N, et al. Skull Base Invasion Patterns of Malignant Head and Neck Tumors: A Neurosurgical Perspective [J]. J Neurol Surg B Skull Base, 2021, 82(Suppl 3): e120-e30.

[22]Zuo F, Ye S, Qian H, et al. Maxillary Swing Approach for Central Skull Base Lesions in Extreme Situations: A Single-Institutional Case Series [J]. World Neurosurg, 2022, 166: e337-e44.

[23]Chung H J, Moon I S, Cho H J, et al. Analysis of Surgical Approaches to Skull Base Tumors Involving the Pterygopalatine and Infratemporal Fossa [J]. J Craniofac Surg, 2019, 30(2): 589-95.

[24]Zanoletti E, Marioni G, Nicolai P, et al. The contribution of oncological lateral skull base surgery to the management of advanced head-neck tumors [J]. Acta Otolaryngol, 2023, 143(2): 101-5.

[25]冯芝恩, 王翀, 秦力铮, 等. 侧颅底肿瘤的手术入路和修复重建 [J]. 北京口腔医学, 2019, 27(03): 147-50.

[26]Kong D S, Kim Y H, Lee W J, et al. Indications and outcomes of endoscopic transorbital surgery for trigeminal schwannoma based on tumor classification: a multicenter study with 50 cases [J]. J Neurosurg, 2022: 1-9.

[27]王源源, 吴国洋, 罗晔哲, 等. 经胸经口联合入路腔镜甲状腺癌颈侧区淋巴结清扫术临床应用 [J]. 中国普通外科杂志, 2022, 31(11): 1437-44.

[28]李兴强, 李淑薇, 刘长阳, 等. 股前外侧皮瓣复合个性化钛网支架在上颌骨缺损修复中的应用 [J]. 现代肿瘤医学, 2023, 31(42): 4551-4.

[29]van Rooij J A F, Roubos J, Vrancken Peeters N, et al. Long-term patient-reported outcomes after reconstructive surgery for head and neck cancer: A systematic review [J]. Head Neck, 2023, 45(9): 2469-77.

[30]张志愿. 口腔颌面外科学 [M]. 人民卫生出版社, 2020.

[31]Holcomb A J, Richmon J D. Robotic and Endoscopic Approaches to Head and Neck Surgery [J]. Hematol Oncol Clin North Am, 2021, 35(5): 875-94.

[32]Saia G, Fusetti S, Emanuelli E, et al. Intraoral endoscopic enucleation of a solitary bone cyst of the mandibular condyle [J]. Int J Oral Maxillofac Surg, 2012, 41(3): 317-20.

[33]Li S H, Wang Y, Huang Z X, et al. Endoscope-assisted Surgery in the Treatment of Dentigerous Cyst Involving the Maxillary Sinus - Report of Two Cases [J]. Chin J Dent Res, 2020, 23(1): 71-6.

[34]Sembronio S, Albiero A M, Zerman N, et al. Endoscopically assisted enucleation and curettage of large mandibular odontogenic keratocyst [J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2009, 107(2): 193-6.

[35]Chen S, Alkebsi K, Xuan M, et al. Single incision-plus approach for gasless endoscopic parotidectomy: a seven-step procedure [J]. Transl Cancer Res, 2022, 11(7): 2462-72.

[36]Golusinski W, Golusinska-Kardach E. Current Role of Surgery in the Management of Oropharyngeal Cancer [J]. Front Oncol, 2019, 9: 388.

[37]Nguyen A T, Luu M, Mallen-St Clair J, et al. Comparison of Survival After Transoral Robotic Surgery vs Nonrobotic Surgery in Patients With Early-Stage Oropharyngeal Squamous Cell Carcinoma [J]. JAMA Oncol, 2020, 6(10): 1555-62.

[38]Park D A, Lee M J, Kim S H, et al. Comparative safety and effectiveness of transoral robotic surgery versus open surgery for oropharyngeal cancer: A systematic review and meta-analysis [J]. Eur J Surg Oncol, 2020, 46(4 Pt A): 644-9.

[39]王旭东, 魏弘朴, 李彪. 从“经验外科”到“精准外科”——精准正颌外科体系的建立与临床应用 [J]. 华西口腔医学杂志, 2023, 41(05): 491-501.

[40]王艳艳, 康非吾. 数字化技术在牙槽外科中的应用及进展 [J]. 口腔颌面外科杂志, 2023, 33(02): 116-8.

[41]何宗轩, 韩红钰, 陈立强, 等. 数字化3D打印模型结合CBL教学在口腔颌面外科实习教学中的应用研究 [J]. 中华医学教育探索杂志, 2023, 22(08): 1211-3.

[42]李劲松, 李群星. 3D打印技术在颌骨精确功能性重建的应用 [J]. 口腔疾病防治, 2023, 31(06): 381-8.

[43]王顺吉, 章文博, 于尧, 等. 术前虚拟设计在股前外侧皮瓣修复口腔颌面部缺损中的应用 [J]. 北京大学学报(医学版), 2020, 52(01): 119-23.

[44]彭歆. 口腔颌面外科领域人工智能的应用现状及存在问题 [J]. 中华口腔医学杂志, 2023, 58(6): 527-32.

[45]Zhong Y W, Jiang Y, Dong S, et al. Tumor radiomics signature for artificial neural network-assisted detection of neck metastasis in patient with tongue cancer [J]. J Neuroradiol, 2022, 49(2): 213-8.

[46]邱蔚六. 邱蔚六口腔颌面外科学 [M]. 上海科学技术出版社, 2008.

[47]Imai T, Asada Y, Matsuura K. Enhanced recovery pathways for head and neck surgery with free tissue transfer reconstruction [J]. Auris Nasus Larynx, 2023, 51(1): 38-50.

[48]Nieminen T, Tapiovaara L, Back L, et al. Enhanced recovery after surgery (ERAS) protocol improves patient outcomes in free flap surgery for head and neck cancer [J]. Eur Arch Otorhinolaryngol, 2024, 281(2): 907-14.

[49]Shinozaki T, Imai T, Kobayashi K, et al. Preoperative steroid for enhancing patients' recovery after head and neck cancer surgery with free tissue transfer reconstruction: protocol for a phase III, placebo-controlled, randomised, double-blind study (J-SUPPORT 2022, PreSte-HN Study) [J]. BMJ Open, 2023, 13(5): e069303.

[50]牛芳桥, 孙沫逸, 肖海鹏, 等. 口腔颌面外科围手术期血糖管理专家共识 [J]. 实用口腔医学杂志, 2022, 38(01): 5-12.

[51]孙沫逸, 郭伟, 冉炜, 等. 口腔颌面外科围手术期静脉血栓栓塞症评估与预防专家共识 [J]. 实用口腔医学杂志, 2021, 37(03): 293-302.

[52]何悦, 蒋灿华, 侯劲松, 等. 穿支皮瓣修复口腔颌面-头颈部缺损专家共识 [J]. 中国口腔颌面外科杂志, 2020, 18(05): 385-9.

[53]朱墨, 金萬勇, 朱载瓯,等. 围手术期凝血指标与口腔颌面部游离皮瓣相关并发症间的关系 [J]. 口腔医学, 2021, 41(06): 521-6.

[54]束明阳, 胡玮玮, 朱晓琴. 围手术期外周血淋巴细胞计数对晚期口腔鳞状细胞癌患者的临床意义 [J]. 口腔颌面外科杂志, 2022, 32(02): 1774-8.

[55]刘璐璐, 李秀川, 袁冯,等. 加速康复外科理念在游离皮瓣修复口腔癌患者中的应用 [J]. 中华全科医学, 2020, 18(10): 1774-8.

[56]Kerawala C, Roques T, Jeannon J P, et al. Oral cavity and lip cancer: United Kingdom National Multidisciplinary Guidelines [J]. J Laryngol Otol, 2016, 130(S2): S83-S9.

[57]Nag S, Cano E R, Demanes D J, et al. The American Brachytherapy Society recommendations for high-dose-rate brachytherapy for head-and-neck carcinoma [J]. Int J Radiat Oncol Biol Phys, 2001, 50(5): 1190-8.

[58]Kovacs G, Martinez-Monge R, Budrukkar A, et al. GEC-ESTRO ACROP recommendations for head & neck brachytherapy in squamous cell carcinomas: 1st update - Improvement by cross sectional imaging based treatment planning and stepping source technology [J]. Radiother Oncol, 2017, 122(2): 248-54.

[59]Pignon J P, Bourhis J, Domenge C, et al. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three meta-analyses of updated individual data. MACH-NC Collaborative Group. Meta-Analysis of Chemotherapy on Head and Neck Cancer [J]. Lancet, 2000, 355(9208): 949-55.

[60]Blanchard P, Baujat B, Holostenco V, et al. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): a comprehensive analysis by tumour site [J]. Radiother Oncol, 2011, 100(1): 33-40.

[61]Lacas B, Carmel A, Landais C, et al. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group [J]. Radiother Oncol, 2021, 156: 281-93.

[62]Posner M R, Hershock D M, Blajman C R, et al. Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer [J]. N Engl J Med, 2007, 357(17): 1705-15.

[63]Lorch J H, Goloubeva O, Haddad R I, et al. Induction chemotherapy with cisplatin and fluorouracil alone or in combination with docetaxel in locally advanced squamous-cell cancer of the head and neck: long-term results of the TAX 324 randomised phase 3 trial [J]. Lancet Oncol, 2011, 12(2): 153-9.

[64]Vermorken J B, Remenar E, van Herpen C, et al. Cisplatin, fluorouracil, and docetaxel in unresectable head and neck cancer [J]. N Engl J Med, 2007, 357(17): 1695-704.

[65]Dovedi S J, Adlard A L, Lipowska-Bhalla G, et al. Acquired resistance to fractionated radiotherapy can be overcome by concurrent PD-L1 blockade [J]. Cancer Res, 2014, 74(19): 5458-68.

[66]Weiss J, Sheth S, Deal A M, et al. Concurrent Definitive Immunoradiotherapy for Patients with Stage III-IV Head and Neck Cancer and Cisplatin Contraindication [J]. Clin Cancer Res, 2020, 26(16): 4260-7.

[67]Lee N Y, Ferris R L, Psyrri A, et al. Avelumab plus standard-of-care chemoradiotherapy versus chemoradiotherapy alone in patients with locally advanced squamous cell carcinoma of the head and neck: a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial [J]. Lancet Oncol, 2021, 22(4): 450-62.

[68]Tao Y, Auperin A, Sun X, et al. Avelumab-cetuximab-radiotherapy versus standards of care in locally advanced squamous-cell carcinoma of the head and neck: The safety phase of a randomised phase III trial GORTEC 2017-01 (REACH) [J]. Eur J Cancer, 2020, 141: 21-9.

[69]Ferris R L. Immunology and Immunotherapy of Head and Neck Cancer [J]. J Clin Oncol, 2015, 33(29): 3293-304.

[70]Kitamura N, Sento S, Yoshizawa Y, et al. Current Trends and Future Prospects of Molecular Targeted Therapy in Head and Neck Squamous Cell Carcinoma [J]. Int J Mol Sci, 2020, 22(1).

[71]Le X, Ferrarotto R, Wise-Draper T, et al. Evolving Role of Immunotherapy in Recurrent Metastatic Head and Neck Cancer [J]. J Natl Compr Canc Netw, 2020, 18(7): 899-906.

[72]Zhong L P, Zhang C P, Ren G X, et al. Randomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma [J]. J Clin Oncol, 2013, 31(6): 744-51.

[73]Huang X, Liu Q, Zhong G, et al. Neoadjuvant toripalimab combined with gemcitabine and cisplatin in resectable locally advanced head and neck squamous cell carcinoma (NeoTGP01): An open label, single-arm, phase Ib clinical trial [J]. J Exp Clin Cancer Res, 2022, 41(1): 300.

[74]Zhang Z, Wu B, Peng G, et al. Neoadjuvant Chemoimmunotherapy for the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma: A Single-Arm Phase 2 Clinical Trial [J]. Clin Cancer Res, 2022, 28(15): 3268-76.

[75]Wu W J, Liu Q, An P G, et al. Neoadjuvant tislelizumab combined with chemotherapy in locally advanced oral or oropharyngeal squamous cell carcinoma: a real-world retrospective study [J]. Front Immunol, 2023, 14: 1282629.

[76]Dou S, Zhang L, Li R, et al. Adjuvant PD-1 antibody in recurrent, previously irradiated oral cavity cancer treated with salvage surgery [J]. Clin Transl Radiat Oncol, 2023, 40: 100623.

[77]Cohen E E W, Bell R B, Bifulco C B, et al. The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC) [J]. J Immunother Cancer, 2019, 7(1): 184.

[78]Freytag M, Herrlinger U, Hauser S, et al. Higher number of multidisciplinary tumor board meetings per case leads to improved clinical outcome [J]. BMC Cancer, 2020, 20(1): 355.

[79]Nocon C C, Ajmani G S, Bhayani M K. Association of Facility Volume With Positive Margin Rate in the Surgical Treatment of Head and Neck Cancer [J]. JAMA Otolaryngol Head Neck Surg, 2018, 144(12): 1090-7.

[80]Adkins C, Takakura W, Spiegel B M R, et al. Prevalence and Characteristics of Dysphagia Based on a Population-Based Survey [J]. Clin Gastroenterol Hepatol, 2020, 18(9): 1970-9 e2.

[81]Banda K J, Chu H, Kang X L, et al. Prevalence of dysphagia and risk of pneumonia and mortality in acute stroke patients: a meta-analysis [J]. BMC Geriatr, 2022, 22(1): 420.

[82]Lindgren S, Janzon L. Prevalence of swallowing complaints and clinical findings among 50-79-year-old men and women in an urban population [J]. Dysphagia, 1991, 6(4): 187-92.

[83]中国吞咽障碍康复评估与治疗专家共识组. 中国吞咽障碍评估与治疗专家共识(2017 年版)第一部分 评估篇 [J]. 中华物理医学与康复杂志, 2017, 39(12): 881-92.

[84]中华口腔医学会口腔颌面-头颈肿瘤专业委员会. 舌黏膜鳞状细胞癌外科治疗的专家共识 [J]. 中华口腔医学杂志, 2022, 57(8): 836-48.

[85]王国民, 朱川, 袁文化. 汉语语音清晰度测试字表的建立和临床应用研究 [J]. 上海口腔医学, 1995, 4(3): 3.

[86]Rinkel R N, Verdonck-de Leeuw I M, van Reij E J, et al. Speech Handicap Index in patients with oral and pharyngeal cancer: better understanding of patients' complaints [J]. Head Neck, 2008, 30(7): 868-74.

[87]汉语失语症康复治疗专家共识组. 汉语失语症康复治疗专家共识 [J]. 中华物理医学与康复杂志, 2019, 41(3): 161-9.

[88]洁 汪, 冰 秦. 失语症恢复机制的神经影像学研究进展 [J]. 中国卒中, 2006, (1): 521-5.

[89]夏娣文, 翟浩瀚, 程薇萍, 等. 计算机语言障碍诊疗系统对脑卒中构音障碍的治疗作用 [J]. 中国康复, 2009, 24(01): 21-2.

[90]冯小欢, 丘卫红, 陈兆聪, 等. 运动性构音障碍患者发音时构音运动学特征:基于电磁发音动作描记仪的研究 [J]. 中国康复理论与实践, 2019, 25(02): 125-34.

[91]李胜利, 张庆苏, 卫冬洁,等. 运动性构音障碍言语、声学及疗效的研究 [J]. 中国康复理论与实践, 2006, (07): 591-2.

[92]周勇, 焦杨, 席家宁, 等. 言语康复构音障碍评定医生助手软件设计与实现 [J]. 中国数字医学, 2021, 16(09): 56-60.

[93]Sawant S, Dugad J, Parikh D, et al. Identification & correlation of bacterial diversity in oral cancer and long-term tobacco chewers- A case-control pilot study [J]. J Med Microbiol, 2021, 70(9).

[94]黄墁珊, 寻春雷. T-scan系统结合数字化模型测量咬合力分布的可靠性和准确性研究 [J]. 中华口腔正畸学杂志, 2020, 27(02): 90-5.

[95]Goncalves T, Schimmel M, van der Bilt A, et al. Consensus on the terminologies and methodologies for masticatory assessment [J]. J Oral Rehabil, 2021, 48(6): 745-61.

[96]陈海薇. 远程监督指导对口腔肿瘤患者术后咀嚼功能康复训练影响的研究 [D]; 中国医科大学, 2020.

[97]Nagata K, Hori S, Mizuhashi R, et al. Efficacy of mandibular manipulation technique for temporomandibular disorders patients with mouth opening limitation: a randomized controlled trial for comparison with improved multimodal therapy [J]. J Prosthodont Res, 2019, 63(2): 202-9.

[98]杨冬叶, 陈莺, 黄紫娴, 等. 颞下颌关节不可复性盘前移位患者的口面肌功能训练 [J]. 护理学杂志, 2021, 36(04): 73-5.

[99]Chee S, Byrnes Y M, Chorath K T, et al. Interventions for Trismus in Head and Neck Cancer Patients: A Systematic Review of Randomized Controlled Trials [J]. Integr Cancer Ther, 2021, 20: 15347354211006474.

[100]罗静, 姚严琦, 徐晨. 口腔种植修复治疗牙列缺损的临床效果及舒适度分析 [J]. 贵州医药, 2020, 44(02): 229-31.

[101]Gu X Y, Chen X B, Jiao T, et al. [Application of negative molds technology based on three-dimensional printing in digital maxillofacial prostheses] [J]. Zhonghua Kou Qiang Yi Xue Za Zhi, 2017, 52(6): 336-41.

[102]周恬, 顾晓宇. 数字化和传统方法制备上颌骨缺损赝复体的效果评价 [J]. 口腔颌面修复学杂志, 2021, 11(22): 430-4.

[103]Khan A J, Szczepura A, Palmer S, et al. Physical therapy for facial nerve paralysis (Bell's palsy): An updated and extended systematic review of the evidence for facial exercise therapy [J]. Clin Rehabil, 2022, 36(11): 1424-49.

[104]Ishii L E. Facial Nerve Rehabilitation [J]. Facial Plast Surg Clin North Am, 2016, 24(4): 573-5.

[105]Si-Yi H, Ling W, Hai-Bo Y, et al. The research for the function evaluation of facial nerve and the mechanisms of rehabilitation training [J]. Medicine (Baltimore), 2021, 100(18): e25430.

[106]Shah K, Patekar S, Ishwarya M, et al. Shoulder Dysfunction Post Spinal Accessory Nerve Preserving Neck Dissections: Our Experience [J]. Indian J Otolaryngol Head Neck Surg, 2023, 75(2): 675-9.

[107]McGarvey A C, Chiarelli P E, Osmotherly P G, et al. Physiotherapy for accessory nerve shoulder dysfunction following neck dissection surgery: a literature review [J]. Head Neck, 2011, 33(2): 274-80.

[108]Mozzini C B, Rodrigues T R, Bergmann A, et al. Adherence to a shoulder dysfunction physical therapy protocol after neck dissection with accessory nerve preservation in head-and-neck cancer patients: An uncontrolled clinical trial [J]. Int J Health Sci (Qassim), 2022, 16(4): 22-9.

[109]Cheng J T, Leite V F, Tennison J M, et al. Rehabilitation Interventions for Head and Neck Cancer-Associated Lymphedema: A Systematic Review [J]. JAMA Otolaryngol Head Neck Surg, 2023, 149(8): 743-53.

[110]Tyker A, Franco J, Massa S T, et al. Treatment for lymphedema following head and neck cancer therapy: A systematic review [J]. Am J Otolaryngol, 2019, 40(5): 761-9.

[111]Parke S C, Langelier D M, Cheng J T, et al. State of Rehabilitation Research in the Head and Neck Cancer Population: Functional Impact vs. Impairment-Focused Outcomes [J]. Curr Oncol Rep, 2022, 24(4): 517-32.

[112]唐丽丽. 中国肿瘤心理临床实践指南(2020) [M]. 北京:人民卫生出版社, 2020.

[113]齐伟静, 胡洁, 李来有. 2018.V1版《NCCN癌症临床指南:心理痛苦的处理》解读 [J]. 中国全科医学, 2018, 21(15): 1765-8.

[114]李惠艳. 护理心理学. 4版 [M]. 北京：人民卫生出版社, 2017.

[115]Melissant H C, Jansen F, Eerenstein S E, et al. Body image distress in head and neck cancer patients: what are we looking at? [J]. Support Care Cancer, 2021, 29(4): 2161-9.

[116]Warburg O. The Chemical Constitution of Respiration Ferment [J]. Science, 1928, 68(1767): 437-43.

[117]于恺英, 王晓琳, 石汉平. 肿瘤营养治疗的发展与进步 [J]. 首都医科大学学报, 2021, 6(42): 499-502.

[118]石汉平, 凌文华, 李薇. 肿瘤营养学 [M]. 北京：人民卫生出版社, 2012.

[119]石汉平. 肿瘤是一种代谢性疾病 [J]. 肿瘤代谢与营养电子杂志, 2018, 5(2): 111-6.

[120]于恺英, 刘俐惠, 石汉平. 营养状况是基本生命体征 [J]. 肿瘤代谢与营养电子杂志, 2019, 6(04): 391-5.

[121]石汉平. 营养治疗是肿瘤的一线治疗 [J]. 临床药物治疗杂志, 2019, 17(4): 20-5.

[122]宋春花;, 王昆华;, 郭增清;, 等. 中国常见恶性肿瘤患者营养状况调查 [J]. 中国科学:生命科学, 2020, 50(12): 1437-52.

[123]Ehrsson Y T, Langius-Eklof A, Laurell G. Nutritional surveillance and weight loss in head and neck cancer patients [J]. Support Care Cancer, 2012, 20(4): 757-65.

[124]Talwar B, Donnelly R, Skelly R, et al. Nutritional management in head and neck cancer: United Kingdom National Multidisciplinary Guidelines [J]. J Laryngol Otol, 2016, 130(S2): S32-S40.